Unpacking Latino Genes to Find Answers for Alzheimer’s Disease



Researchers are exploring a genetic variant that could explain the higher rates of Alzheimer’s among Latinos living in Puerto Rico. This work – which is ongoing – could help fill a critical gap in Latino Alzheimer’s research and spark new treatments for dementia, according to researchers at the John P. Hussman Institute for Human Genomics at the University of Miami. “A genetic target, which drug companies are showing interest in, is twice as likely to be successful therapeutically than nongenetic targets,” Margaret Pericak-Vance, leader of the Hussman Institute, told NBC News. Let’s dive into the research and how it impacts Latinos! The Need for Genetic Research on Alzheimer’s among Latinos Latinos are 1.5 times more likely than their peers to have ...

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Webinar Series: Let’s Address Health Equity Together


Webinar Series Let’s Address Health Equity Together

Health equity is where everyone has a fair, just opportunity to be healthier. How can we reach this ideal, especially as Latinos face cancer and chronic disease health disparities rooted in systemic inequities in access to clinical trials, income, health care, food, housing, and discrimination? You're invited to a webinar series, "Let’s Address Health Equity Together," a collaboration of the Salud America! program at the Institute for Health Promotion Research at UT Health San Antonio, the Mays Cancer Center at UT Health San Antonio, and Genentech. Here are the three webinars planned for 2024: 4/25/24: How to Identify and Equitably Respond to Local Cancer Needs 7/15/24: How to Support Latino Cancer Survivors 9/10/24: How to Fight Back Against El Asesino ...

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Latinos, Help Researchers Understand How Social Factors Affect Rheumatoid Arthritis!


RA doc

Rheumatoid arthritis (RA) can be debilitating and place a significant burden on patients, their families, employers, and the government. While genetics and health inequities do play a role in the development and progression of RA, social issues, such as lack of family and friend support, can also play a role in the progression of the disease. Researchers at the National Institutes of Health (NIH) Clinical Center want to learn more about how social and genetic factors affect RA in Latinos, who often face social issues when it comes to health. You can help by participating in a clinical trial no matter where you live in the US! Rheumatoid Arthritis Study Qualifications To be eligible for this clinical trial, you must be age 18 or older and of Hispanic/Latino heritage. You may ...

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Study: Phase 1 Cancer Treatment Clinical Trials May Offer More Benefits Than in Past


clinical trials phase 1

Clinical trials are studies with volunteers that help researchers learn how to slow, manage, and treat different diseases. There are four phases of clinical trials that each help scientists answer different questions. Phase 1 clinical trials are the first step in testing a new treatment in people. They focus on evaluating the safety, side effects, best dose, and timing of a new treatment, according to the National Cancer Institute (NCI). Phase 1 clinical trials usually include a small number of patients who have not been helped by other treatments. In the past, participants in phase 1 trials for cancer treatment generally had low tumor response rates. And, because phase 1 trials are focused on assessing safety of treatments, doctors have hesitated to refer patients to these ...

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Help Researchers Learn More about Preventing Dementia, Disability, and Disease


Patient and doctor

If you’re age 75 or older, you should know about PREVENTABLE. PREVENTABLE – the Pragmatic Evaluation of events And Benefits of Lipid-lowering – is a clinical trial to help researchers understand if taking a statin, a drug commonly used to lower cholesterol in younger adults, is helpful for older adults, specifically when it comes to maintaining health by preventing dementia, disability, and heart disease. “We really don’t know how these drugs work in older adults,” according to the research team at UT Health San Antonio, including Dr. Sara Espinoza, principal investigator for the local study site. “Most, if not all, of the studies of statins have been done in much younger people, in their 50s and 60s, but studies in adults over 75 are rare.” The national study is ...

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Cancer Clinical Trials: 2022 Advancing the Science of Cancer in Latinos


latina doctor patient clinical trials

This is part of the "Advancing the Science of Cancer in Latinos: 2022 Conference Proceedings," which summarizes findings and discussions of the 2022 Advancing the Science of Cancer in Latinos Conference on Feb. 23-25, 2022, in San Antonio, Texas. Novel Therapeutic Approach to Reduce Health Disparity in B-cell Acute Lymphoblastic Leukemia in Hispanic/Latino Children Dr. Sinisa Dovat is Professor of Pediatrics, Pharmacology, and Biochemistry and Molecular Biology at Pennsylvania State University College of Medicine. He is also Four Diamond Endowed Chair and Director of Translational Research and Experimental Therapeutics in Pediatric Hematology/Oncology at Penn State University. B-Cell acute lymphoblastic leukemia and Hispanic children B-Cell acute lymphoblastic leukemia (B-ALL) ...

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Go Fish! Study Connects Omega-3s to Brain Health Improvement at Midlife


Omega-3 options

Consuming cold-water fish and other sources of omega-3 fatty acids could preserve brain health and enhance cognition in middle age, according to a recent study led by researchers at UT Health San Antonio and the Framingham Heart Study. “Our results, albeit exploratory, suggest that higher omega-3 fatty acid concentrations are related to better brain structure and cognitive function in a predominantly middle-aged cohort free of clinical dementia,” according to the study. What Are Omega-3s? Omega-3s are a family of essential fatty acids that play an important role in the human body. “Although evidence is mixed, studies indicate that omega-3 fatty acids can protect against all sorts of illnesses, including breast cancer, depression, ADHD, and various inflammatory diseases,” ...

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UNITE Initiative Responds to Dr. Amelie Ramirez’s Comment on Racial Equity, Diversity


ndorse Dr. Amelie Ramirez’s Comment on Racial Equity and Diversity in Research!

The National Institutes of Health's UNITE initiative has responded to over 1,100 comments, including one from Dr. Amelie Ramirez of Salud America! and UT Health San Antonio, calling for racial equity and diversity in research. UNITE sought comments in spring 2021. Ramirez submitted a comment—endorsed by 541 Salud America! members—that we believe that increasing diversity among research leaders and clinical trial participants will help achieve true health equity, especially for Latinos and others disproportionately impacted by health issues. Based on these comments, the UNITE initiative formulated four priority areas in health disparities and minority health research, the internal NIH workforce, and the external research workforce. "Here at NIH, we saw with fresh eyes the ...

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Is a Clinical Trial Right for Your Child?


Doctor discussing clinical trial

We all want the best for our children. While the thought of enrolling your child in a clinical trial may sound scary, but there are plenty of benefits to trial participation. Some of these benefits include diagnosing, preventing, treating, and sometimes even curing childhood diseases. However, there are some potential risks to trial participation, too. Here’s everything you need to know about enrolling your child in a clinical trial. What is a Clinical Trial? Clinical trials are studies with volunteers that help researchers learn how to slow, manage, and treat different diseases. There are different kinds of clinical trials with different intended purposes. There are also four phases of clinical trials that each help scientists answer different ...

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