Researchers from UT Health San Antonio have tied obesity to with 21 Alzheimer’s disease-related genes. In analyzing 74 Alzheimer’s-related genes from the Framingham Heart Study, researchers found that 21 of them were either under-expressed or over-expressed in obesity. “Several of the genes were more strongly related to obesity in midlife versus in late life, and also to obesity in women versus men,” said Dr. Claudia Satizabal, study lead author and assistant professor of population health sciences at UT Health San Antonio.
Alzheimer’s Genes Linked to Obesity
The UT Health San Antonio study also found 13 Alzheimer’s-related genes were associated with body mass index (BMI) and eight genes associated with a second metric of obesity called waist-to-hip ratio. “Those ...
Researchers are exploring a genetic variant that could explain the higher rates of Alzheimer’s among Latinos living in Puerto Rico. This work – which is ongoing – could help fill a critical gap in Latino Alzheimer’s research and spark new treatments for dementia, according to researchers at the John P. Hussman Institute for Human Genomics at the University of Miami. “A genetic target, which drug companies are showing interest in, is twice as likely to be successful therapeutically than nongenetic targets,” Margaret Pericak-Vance, leader of the Hussman Institute, told NBC News. Let’s dive into the research and how it impacts Latinos!
The Need for Genetic Research on Alzheimer’s among Latinos
Latinos are 1.5 times more likely than their peers to have ...
If you’re age 75 or older, you should know about PREVENTABLE. PREVENTABLE – the Pragmatic Evaluation of events And Benefits of Lipid-lowering – is a clinical trial to help researchers understand if taking a statin, a drug commonly used to lower cholesterol in younger adults, is helpful for older adults, specifically when it comes to maintaining health by preventing dementia, disability, and heart disease. “We really don’t know how these drugs work in older adults,” according to the research team at UT Health San Antonio, including Dr. Sara Espinoza, principal investigator for the local study site. “Most, if not all, of the studies of statins have been done in much younger people, in their 50s and 60s, but studies in adults over 75 are rare.” The national study is ...
Consuming cold-water fish and other sources of omega-3 fatty acids could preserve brain health and enhance cognition in middle age, according to a recent study led by researchers at UT Health San Antonio and the Framingham Heart Study. “Our results, albeit exploratory, suggest that higher omega-3 fatty acid concentrations are related to better brain structure and cognitive function in a predominantly middle-aged cohort free of clinical dementia,” according to the study.
What Are Omega-3s?
Omega-3s are a family of essential fatty acids that play an important role in the human body. “Although evidence is mixed, studies indicate that omega-3 fatty acids can protect against all sorts of illnesses, including breast cancer, depression, ADHD, and various inflammatory diseases,” ...
Alzheimer’s patients and their loved ones have new reason for hope after positive results from clinical trial of a new treatment called lecanemab. Lecanemab – a drug designed to slow the progression of Alzheimer’s disease by targeting amyloid plaque buildup in the brain – reduced the progression of cognitive decline among trial participants by 27% over 18 months, compared to placebo, according to UsAgainstAlzheimers. “This is very important and quite positive news that gives our nation’s 6 million Alzheimer’s patients and their loved ones reason to hope again. In fact, the data is a reminder that each drug in this class of therapies is quite different,” said George Vradenburg, chair and co-founder of UsAgainstAlzheimers. What do the results show, and how will ...
By 2030, 40% of Alzheimer’s patients in the U.S. will be Latino or Black. However, Latinos make up less than 1% of participants in National Institutes of Health clinical trials. Clinical trials are studies that help researchers learn more to help slow, manage, and treat Alzheimer’s and cancer for current and future family members. Without Latino volunteers for clinical trials, the benefits may miss this group. With Compadre CART at the Biggs Institute for Alzheimer’s & Neurodegenerative Diseases at UT Health San Antonio participants have the opportunity to help an underrepresented, high-risk group maintain independence with aging. To participate, contact Luis Serranorubio of the research team at 210-450-8447.
Compadre CART Study Goals
To learn more about why ...
From merengue to salsa, dance and music are at the heart of the Latino community. Latin dance celebrates culture, history, family, and joyous occasions. Now Latin dance is proving to help the working memory of older Latinos. Latinos age 55 or older who participated in a culturally relevant Latin dance program for 8 months significantly improved their working memory, compared to other peers in a controlled group that attended educational workshops, according to a recent study by researchers from the University of Illinois Urbana-Champaign. Let’s explore why Latin dance is so beneficial.
What Did the Latin Dance Study Explore?
The recent study examined changes in cognitive performance among over 330 middle-aged and older Latinos participating in the Balance and Activity in ...
Caregivers are a lifeline for people living with dementia. But who is the lifeline for caregivers? The Caring for the Caregivers program at UT Health San Antonio serves as a resource and support for patient caregivers and families through evidence-based education and research. “We envision a community where family caregivers are valued, respected, and supported with compassion. We are committed to values of social justice, collaboration, and family-centeredness in research and practice,” according to the Caring for Caregivers webpage. Learn about the programs, events, and tools that can help your family!
Latino Caregivers by the Number
Latinos are greatly impacted by dementia. About 13% of Latinos who are 65 or older have Alzheimer’s or another form of dementia, ...
Researchers at UC Davis Health and the University of Texas Health Science Center at Houston (UTHealth Houston) are working on a new study to predict who is most at risk for dementia or Alzheimer’s disease. The study includes creating a health ‘scorecard’ for dementia risk. Here’s what you need to know about the study and how you can participate.
Study Goal
UT Health San Antonio will be the clinical research site for the Diverse Vascular Contributions to Cognitive Impairment and Dementia (Diverse VCID) study. Data will be collected through brain scans, genetics, and other key biomarkers. “Putting these very different pieces of information together, our ultimate goal is to really come up with a risk profile,” Dr. Charles DeCarli, Professor of Neurology and ...
